Estrogen Dominance
Estrogen dominance is not just having too much estrogen. It is when you have too much estrogen compared to progesterone. The causes come from your gut, liver, genes, and the world around you.
Estrogen dominance happens when estrogen gets too high compared to progesterone. This can occur from making too much estrogen, a liver that does not clean it out well, gut bacteria that send estrogen back into the body, or chemicals from the environment that act like estrogen. Signal-Based Medicine uses DUTCH testing to measure how the body breaks down estrogen and clears it out. This test shows the link between hormone imbalance and gut health, how your genes handle cleaning toxins, and environmental factors.
Symptoms
Weight gain settling in your hips, thighs, and belly. Mood swings and irritability that catch you off guard. Periods that are heavy or painful. Breasts that feel tender to the touch. Bloating and water retention that makes your clothes fit differently. A fatigue that sits on you. Brain fog when you need to think straight. Growths in the uterus that cause pain and bleeding. A drop in interest in sex. Nights when sleep won't come or won't stay.
Root Causes
Your body makes estrogen, uses it, and should clear it out through your liver and gut. But if your liver is slow at cleaning things out, or if your gut bacteria wake up estrogen that was supposed to leave your body, the estrogen goes back into your blood. Fake estrogen from plastics and soaps adds more. Stress uses up progesterone to make cortisol instead. Now you have too much estrogen coming at you from many directions.
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Testing
A hormone test that shows estrogen and how your body breaks it down. A gut bacteria test that checks one specific enzyme. Liver health markers. A test for poisons from outside your body. Your genes for cleaning out toxins. KureBioMap assessment.

Treatment Approach
We find every way your body makes too much estrogen. This happens in your liver, your gut, and from stress and things around you. Then we build a plan to fix how your body handles estrogen and balance it with progesterone.
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Frequently Asked Questions
Can men have too much estrogen?
Yes. Men can get too much estrogen from chemicals in the environment, being overweight, a liver that does not work right, and gut bacteria problems. It shows up as weight gain, low sex drive, tiredness, and mood swings.
Will progesterone cream fix estrogen dominance?
It may help for a little while, but it does not fix why estrogen got too high in the first place. Your liver might not be clearing it out. Your gut might be sending it back into your blood. You might be getting it from the world around you. Until you fix one of those things, the real problem stays.
How do chemicals in the world around us cause too much estrogen?
Fake estrogens hide in plastics, soaps, and bug sprays. Your body reads them as real estrogen. They pile up inside you, and your body cannot control them the way it controls real estrogen.
About the author
Kenton Gray is the Founder and Chief Executive Officer of Kure Health. He writes here as an operator, not a clinician.


