Lyme Disease
Chronic Lyme disease is one of the most misunderstood and under-diagnosed conditions in medicine. Standard two-tier testing (ELISA followed by Western Blot) misses up to 50% of cases, and most practitioners are unaware that Lyme co-infections can cause more symptoms than Lyme itself.
Chronic Lyme disease and co-infections create persistent immune activation, neurological inflammation, and multi-system dysfunction that standard testing frequently misses. Signal-Based Medicine™ evaluates the complete infection burden, immune response patterns, detoxification capacity, and downstream effects on hormones, gut health, and neurological function through the KureBioMap™.
Symptoms
- Migrating joint pain
- Fatigue
- Brain fog and memory problems
- Numbness and tingling
- Bell's palsy or facial drooping
- Heart palpitations
- Night sweats
- Anxiety and mood changes
- Headaches
- Muscle twitching
Root Causes
Lyme spirochetes are master evaders. They form biofilms, change surface proteins, and suppress immune detection. Standard testing looks for antibodies your body may never have produced because the organism suppressed the response. Co-infections often cause MORE symptoms than Lyme itself. A complete picture requires specialty testing and evaluation of the entire immune-neurological-hormonal cascade.
Testing
- Specialty Lyme panel (not standard ELISA alone)
- Co-infection panel
- CD57 NK cell count
- Inflammatory markers
- Neurological evaluation
- Hormonal assessment
- KureBioMap™ assessment
Treatment Approach
We evaluate the complete infection burden including co-infections, assess immune function, and build targeted antimicrobial protocols while supporting detoxification, immune recovery, and neurological repair — all guided by KureBioMap™ data.
Frequently Asked Questions
Can Lyme disease be chronic? Yes. Despite controversy, mounting evidence shows Borrelia can persist in tissues despite standard antibiotic treatment, particularly when co-infections and biofilms are not addressed.
Why was my Lyme test negative? Standard two-tier testing misses up to 50% of cases. It relies on antibody production, which can be suppressed by the organism itself. Specialty testing using different methodologies is often needed.
What are co-infections? Ticks that carry Lyme often carry additional organisms — Babesia, Bartonella, Ehrlichia, and others. These co-infections can cause symptoms that are different from and sometimes worse than Lyme itself, and they require different treatments.
How long does treatment take? Treatment duration varies based on infection burden, co-infections present, and how long you've been ill. Most members require several months of comprehensive treatment. We track progress through objective markers and KureBioMap™ reassessments.

