Is hormone replacement therapy safe?

Bioidentical hormone therapy, properly monitored and personalized based on comprehensive testing (including genetic hormone metabolism), can be safe and effective for many women. The key is individualization — not one-size-fits-all prescribing.

When should I start addressing menopause symptoms?

Ideally during perimenopause, before symptoms become severe. Early assessment allows us to optimize adrenal reserve, thyroid function, and gut health — systems that determine how smoothly the menopausal transition goes.

Can I manage menopause without hormones?

Some women can, depending on their adrenal reserve, thyroid function, and overall health status. Our assessment identifies whether hormonal support is needed or if other system optimization can adequately manage symptoms.

Conditions We Treat

Menopause & Perimenopause

Menopause is natural. Suffering through it is not. The severity of your symptoms depends not just on declining ovarian hormones but on how well your other systems — adrenals, thyroid, gut, liver — can compensate. Most HRT protocols ignore all of this.

Perimenopause and menopause involve the progressive decline of ovarian hormone production — but the severity of symptoms depends on adrenal reserve, thyroid compensation, gut estrogen metabolism, stress load, and genetic hormone processing pathways. Signal-Based Medicine™ evaluates the complete hormonal ecosystem through DUTCH testing and the KureBioMap™, providing targeted support rather than one-size-fits-all HRT.

Common Symptoms

Does this sound like you? These symptoms may seem unrelated — but they share common root signals.

Hot flashes and night sweats

Mood changes and irritability

Sleep disruption

Weight gain (especially midsection)

Brain fog

Low libido

Vaginal dryness

Joint pain

Hair thinning

Fatigue

The Signal-Based Medicine Perspective

Root Causes of Menopause & Perimenopause

When your ovaries reduce hormone production, your adrenals are supposed to pick up some of the slack. But if your adrenals are already depleted from years of chronic stress, compensation fails. Your gut bacteria metabolize estrogen — if your microbiome is disrupted, estrogen clearance changes. Thyroid function often declines simultaneously. Generic HRT addresses ONE of these systems. We assess all of them.

Declining ovarian hormone production
Adrenal insufficiency (can't compensate)
Thyroid dysfunction
Gut microbiome changes affecting estrogen metabolism
Genetic variants in hormone processing
Chronic stress depleting progesterone

Advanced Diagnostics

How Kure Health Tests for Menopause & Perimenopause

DUTCH complete hormone panel

Adrenal function assessment

Complete thyroid panel

GI-MAP

Bone density markers

Cardiovascular risk markers

Genetic hormone metabolism variants

KureBioMap™ assessment

Treatment

How Kure Health Treats Menopause & Perimenopause

We evaluate your complete hormonal ecosystem — not just estrogen — and build a targeted protocol that may include bioidentical hormones, adrenal support, thyroid optimization, and gut restoration, personalized to your genetics and current state.